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The Potential of Avian H1N1 Influenza A Viruses to Replicate and Cause Disease in Mammalian Models

H1N1 viruses in which all gene segments are of avian origin are the most frequent cause of influenza pandemics in humans; therefore, we examined the disease-causing potential of 31 avian H1N1 isolates of American lineage in DBA/2J mice. Thirty of 31 isolates were very virulent, causing respiratory t...

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Detalhes bibliográficos
Main Authors: Koçer, Zeynep A., Krauss, Scott, Stallknecht, David E., Rehg, Jerold E., Webster, Robert G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404991/
https://ncbi.nlm.nih.gov/pubmed/22848544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041609
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