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An RGD Motif Present in Cadherin 17 Induces Integrin Activation and Tumor Growth
Little is known about the mechanism of integrin activation by cadherin 17 (CDH17). Here we observed the presence of a tri-peptide motif, RGD, in domain 6 of the human CDH17 sequence and other cadherins such as cadherin 5 and cadherin 6. The use of CDH17 RAD mutants demonstrated a considerable decrea...
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| Udgivet i: | J Biol Chem |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4263880/ https://ncbi.nlm.nih.gov/pubmed/25336636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.600502 |
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