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Histone Deacetylase 3 Is Necessary for Proper Brain Development

The functional role of histone deacetylase 3 (HDAC3) in the developing brain has yet to be elucidated. We show that mice lacking HDAC3 in neurons and glia of the central nervous system, Nes-Cre/HDAC3 conditional KO mice, show major abnormalities in the cytoarchitecture of the neocortex and cerebellu...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Norwood, Jordan, Franklin, Jade M., Sharma, Dharmendra, D'Mello, Santosh R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263864/
https://ncbi.nlm.nih.gov/pubmed/25339172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.576397
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