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Abieslactone Induces Cell Cycle Arrest and Apoptosis in Human Hepatocellular Carcinomas through the Mitochondrial Pathway and the Generation of Reactive Oxygen Species

Abieslactone is a triterpenoid lactone isolated from Abies plants. Previous studies have demonstrated that its derivative abiesenonic acid methyl ester possesses anti-tumor-promoting activity in vitro and in vivo. In the present study, cell viability assay demonstrated that abieslactone had selectiv...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:PLoS One
Κύριοι συγγραφείς: Wang, Guo-Wei, Lv, Chao, Shi, Zhi-Ran, Zeng, Ren-Tao, Dong, Xue-Yun, Zhang, Wei-Dong, Liu, Run-Hui, Shan, Lei, Shen, Yun-Heng
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2014
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263740/
https://ncbi.nlm.nih.gov/pubmed/25502685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115151
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