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Effects of daidzein in regards to cytotoxicity in vitro, apoptosis, reactive oxygen species level, cell cycle arrest and the expression of caspase and Bcl-2 family proteins

In the present study, the in vitro cytotoxicity of daidzein was evaluated in human BEL-7402, A549, HeLa, HepG-2 and MG-63 cancer cell lines. BEL-7402 cells were sensitive to daidzein treatment, with an IC(50) value of 59.7±8.1 µM. Daidzein showed no cytotoxic activity toward A549, HeLa, HepG-2 and M...

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Detalhes bibliográficos
Publicado no:Oncol Rep
Main Authors: HAN, BING-JIE, LI, WEI, JIANG, GUANG-BIN, LAI, SHANG-HAI, ZHANG, CHENG, ZENG, CHUAN-CHUAN, LIU, YUN-JUN
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4530929/
https://ncbi.nlm.nih.gov/pubmed/26178389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2015.4133
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