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Mismatch repair status and outcomes after adjuvant therapy in patients with surgically staged endometrial cancer

OBJECTIVES: To determine whether DNA mismatch repair (MMR) modifies the response to chemotherapy or radiotherapy in patients with endometrial cancer. METHODS: Immunohistochemistry (IHC) for the DNA MMR proteins MLH1, MSH2, MSH6, and PMS2 was performed on a tissue microarray of specimens of primary e...

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Detalhes bibliográficos
Publicado no:Gynecol Oncol
Main Authors: Resnick, Kimberly E., Frankel, Wendy L., Morrison, Carl D., Fowler, Jeffrey M., Copeland, Larry J., Stephens, Julie, Kim, Kenneth H., Cohn, David E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263283/
https://ncbi.nlm.nih.gov/pubmed/20153885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2009.12.028
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