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TM6SF2 and MAC30, new enzyme homologs in sterol metabolism and common metabolic disease

Carriers of the Glu167Lys coding variant in the TM6SF2 gene have recently been identified as being more susceptible to non-alcoholic fatty liver disease (NAFLD), yet exhibit lower levels of circulating lipids and hence are protected against cardiovascular disease. Despite the physiological importanc...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Sanchez-Pulido, Luis, Ponting, Chris P.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263179/
https://ncbi.nlm.nih.gov/pubmed/25566323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2014.00439
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