Pharmacokinetics and pharmacodynamics of tiotropium solution and tiotropium powder in chronic obstructive pulmonary disease

The aim of the study was to characterize pharmacokinetics of tiotropium solution 5 µg compared to powder 18 µg and assess dose-dependency of tiotropium solution pharmacodynamics in comparison to placebo. In total 154 patients with chronic obstructive pulmonary disease (COPD) were included in this mu...

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Vydáno v:J Clin Pharmacol
Hlavní autoři: Hohlfeld, JM, Sharma, A, van Noord, JA, Cornelissen, PJG, Derom, E, Towse, L, Peterkin, V, Disse, B
Médium: Artigo
Jazyk:Inglês
Vydáno: BlackWell Publishing Ltd 2014
Témata:
Pharmacokinetics/Pharmacodynamics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263162/
https://ncbi.nlm.nih.gov/pubmed/24165906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.215
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