Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity

In mammalian systems RNA can move between cells via vesicles. Here we demonstrate that the gastrointestinal nematode Heligmosomoides polygyrus, which infects mice, secretes vesicles containing microRNAs (miRNAs) and Y RNAs as well as a nematode Argonaute protein. These vesicles are of intestinal ori...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Buck, Amy H., Coakley, Gillian, Simbari, Fabio, McSorley, Henry J., Quintana, Juan F., Le Bihan, Thierry, Kumar, Sujai, Abreu-Goodger, Cei, Lear, Marissa, Harcus, Yvonne, Ceroni, Alessandro, Babayan, Simon A., Blaxter, Mark, Ivens, Alasdair, Maizels, Rick M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263141/
https://ncbi.nlm.nih.gov/pubmed/25421927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6488
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados