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Hyperosmolar Stress Induces Neutrophil Extracellular Trap Formation: Implications for Dry Eye Disease

PURPOSE. To determine if hyperosmolar stress can stimulate human neutrophils to form neutrophil extracellular traps (NETs) and to investigate potential strategies to reduce formation of NETs (NETosis) in a hyperosmolar environment. METHODS. Neutrophils were isolated from peripheral venous blood of h...

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Publicat a:Invest Ophthalmol Vis Sci
Autors principals: Tibrewal, Sapna, Ivanir, Yair, Sarkar, Joy, Nayeb-Hashemi, Neema, Bouchard, Charles S., Kim, Eunjae, Jain, Sandeep
Format: Artigo
Idioma:Inglês
Publicat: The Association for Research in Vision and Ophthalmology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263134/
https://ncbi.nlm.nih.gov/pubmed/25406284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-15332
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