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A method for inverse bifurcation of biochemical switches: inferring parameters from dose response curves

BACKGROUND: Within cells, stimuli are transduced into cell responses by complex networks of biochemical reactions. In many cell decision processes the underlying networks behave as bistable switches, converting graded stimuli or inputs into all or none cell responses. Observing how systems respond t...

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Detalhes bibliográficos
Publicado no:BMC Syst Biol
Main Authors: Otero-Muras, Irene, Yordanov, Pencho, Stelling, Joerg
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263113/
https://ncbi.nlm.nih.gov/pubmed/25409687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-014-0114-2
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