L-GILZ binds p53 and MDM2 and suppresses tumor growth through p53 activation in human cancer cells

The transcription factor p53 regulates the expression of genes crucial for biological processes such as cell proliferation, metabolism, cell repair, senescence and apoptosis. Activation of p53 also suppresses neoplastic transformations, thereby inhibiting the growth of mutated and/or damaged cells....

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cell Death Differ
Main Authors: Ayroldi, E, Petrillo, M G, Bastianelli, A, Marchetti, M C, Ronchetti, S, Nocentini, G, Ricciotti, L, Cannarile, L, Riccardi, C
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2015
Teme:
Original Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4262776/
https://ncbi.nlm.nih.gov/pubmed/25168242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.129
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