L-GILZ binds p53 and MDM2 and suppresses tumor growth through p53 activation in human cancer cells

The transcription factor p53 regulates the expression of genes crucial for biological processes such as cell proliferation, metabolism, cell repair, senescence and apoptosis. Activation of p53 also suppresses neoplastic transformations, thereby inhibiting the growth of mutated and/or damaged cells....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Death Differ
Prif Awduron: Ayroldi, E, Petrillo, M G, Bastianelli, A, Marchetti, M C, Ronchetti, S, Nocentini, G, Ricciotti, L, Cannarile, L, Riccardi, C
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2015
Pynciau:
Original Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4262776/
https://ncbi.nlm.nih.gov/pubmed/25168242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.129
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