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G-CSF ameliorates neuronal apoptosis through GSK-3β inhibition in neonatal hypoxia–ischemia in rats

Granulocyte-colony stimulating factor (G-CSF), a growth factor, has known neuroprotective effects in a variety of experimental brain injury models. Herein we show that G-CSF administration attenuates neuronal apoptosis after neonatal hypoxia-ischemia (HI) via glycogen synthase kinase-3β (GSK-3β) inh...

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Detalhes bibliográficos
Publicado no:Exp Neurol
Main Authors: Li, Li, Klebe, Damon, Doycheva, Desislava, McBride, Devin W., Krafft, Paul R., Flores, Jerry, Zhou, Changman, Zhang, John H., Tang, Jiping
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4262712/
https://ncbi.nlm.nih.gov/pubmed/25448005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2014.10.004
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