In-Line Separation by Capillary Electrophoresis Prior to Analysis by Top-Down Mass Spectrometry Enables Sensitive Characterization of Protein Complexes

[Image: see text] Intact protein analysis via top-down mass spectrometry (MS) provides a bird’s eye view over the protein complexes and complex protein mixtures with the unique capability of characterizing protein variants, splice isoforms, and combinatorial post-translational modifications (PTMs)....

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Bibliografiska uppgifter
I publikationen:J Proteome Res
Huvudupphovsmän: Han, Xuemei, Wang, Yueju, Aslanian, Aaron, Fonslow, Bryan, Graczyk, Beth, Davis, Trisha N., Yates, John R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Chemical Society 2014
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4262260/
https://ncbi.nlm.nih.gov/pubmed/25382489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr500971h
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