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Decreased muscle glucose transport/phosphorylation is an early defect in the pathogenesis of non-insulin-dependent diabetes mellitus.

Recent studies have demonstrated that reduced insulin-stimulated muscle glycogen synthesis is the major cause of insulin resistance in patients with non-insulin-dependent diabetes mellitus (NIDDM). This reduced rate has been assigned to a defect in either glucose transport or hexokinase activity. Ho...

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Detalhes bibliográficos
Main Authors: Rothman, D L, Magnusson, I, Cline, G, Gerard, D, Kahn, C R, Shulman, R G, Shulman, G I
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC42621/
https://ncbi.nlm.nih.gov/pubmed/7862678
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