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Walking deficits and centrophobism in an α-synuclein fly model of Parkinson's disease1

Parkinson's disease (PD) is a movement neurodegenerative disorder, characterized by bradykinesia, rigidity and tremor, constituting difficulties in walking and abnormal gait. Previous research shows that Drosophila expressing human α-synuclein A30P (A30P) develop deficits in geotaxis climbing;...

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Détails bibliographiques
Publié dans:Genes Brain Behav
Auteurs principaux: Chen, A Y, Wilburn, P, Hao, X, Tully, T
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing Ltd 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4262005/
https://ncbi.nlm.nih.gov/pubmed/25113870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/gbb.12172
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