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Quantitative Organelle Proteomics of MCF-7 Breast Cancer Cells Reveals Multiple Subcellular Locations for Proteins in Cellular Functional Processes

We have combined sucrose density gradient subcellular fractionation with quantitative, tandem-mass-spectrometry-based shotgun proteomics to investigate spatial distributions of proteins in MCF-7 breast cancer cells. Emphasis was placed on four major organellar compartments: cytosol, plasma membrane,...

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Détails bibliographiques
Publié dans:J Proteome Res
Auteurs principaux: Qattan, Amal T., Mulvey, Claire, Crawford, Mark, Natale, Darren A., Godovac-Zimmermann, Jasminka
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4261601/
https://ncbi.nlm.nih.gov/pubmed/19911851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr9008332
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