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c-FLIP is involved in tumor progression of peripheral T-cell lymphoma and targeted by histone deacetylase inhibitors

BACKGROUND: Peripheral T-cell lymphomas (PTCLs) are often aggressive tumors and resistant to conventional chemotherapy. Dysregulation of extrinsic apoptosis plays an important role on tumor cell sensitivity to chemotherapeutic agents. Cellular FLICE inhibitory protein (c-FLIP) is a key regulator of...

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Detalhes bibliográficos
Publicado no:J Hematol Oncol
Main Authors: Zheng, Zhong, Cheng, Shu, Wu, Wen, Wang, Li, Zhao, Yan, Shen, Yang, Janin, Anne, Zhao, Wei-Li
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4261569/
https://ncbi.nlm.nih.gov/pubmed/25477070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-014-0088-y
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