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Modeling T cell receptor recognition of CD1-lipid and MR1-metabolite complexes

BACKGROUND: T cell receptors (TCRs) can recognize diverse lipid and metabolite antigens presented by MHC-like molecules CD1 and MR1, and the molecular basis of many of these interactions has not been determined. Here we applied our protein docking algorithm TCRFlexDock, previously developed to perfo...

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Publicat a:BMC Bioinformatics
Autors principals: Pierce, Brian G, Vreven, Thom, Weng, Zhiping
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4261541/
https://ncbi.nlm.nih.gov/pubmed/25260513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-15-319
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