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Prediction of protein–protein binding free energies

We present an energy function for predicting binding free energies of protein–protein complexes, using the three-dimensional structures of the complex and unbound proteins as input. Our function is a linear combination of nine terms and achieves a correlation coefficient of 0.63 with experimental me...

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Detalhes bibliográficos
Main Authors: Vreven, Thom, Hwang, Howook, Pierce, Brian G, Weng, Zhiping
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375440/
https://ncbi.nlm.nih.gov/pubmed/22238219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2027
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