Maternal allergy increases susceptibility to offspring allergy in association with Th2 biased epigenetic alterations in a mouse model of peanut allergy

BACKGROUND: Although maternal atopy is a risk factor for development of peanut allergy, this phenomenon has not been well-characterized experimentally, and the mechanisms underlying offspring risk are unclear. OBJECTIVE: To determine if offspring of peanut allergic mothers (O-PAM) are more susceptib...

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Publicado en:J Allergy Clin Immunol
Autores principales: Song, Ying, Liu, Changda, Hui, Yiqun, Srivastava, Kamal, Zhou, Zhenwen, Chen, Jia, Miller, Rachel L., Finkelman, Fred D., Li, Xiu-Min
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4261001/
https://ncbi.nlm.nih.gov/pubmed/25441650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2014.08.034
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