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Discovery of a class of endogenous mammalian lipids with anti-diabetic and anti-inflammatory effects

Increased adipose tissue lipogenesis is associated with enhanced insulin sensitivity. Mice overexpressing the Glut4 glucose transporter in adipocytes have elevated lipogenesis and increased glucose tolerance despite being obese with elevated circulating fatty acids. Lipidomic analysis of adipose tis...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Yore, Mark M., Syed, Ismail, Moraes-Vieira, Pedro M., Zhang, Tejia, Herman, Mark A., Homan, Edwin, Patel, Rajesh T., Lee, Jennifer, Chen, Shili, Peroni, Odile D., Dhaneshwar, Abha, Hammarstedt, Ann, Smith, Ulf, McGraw, Timothy E., Saghatelian, Alan, Kahn, Barbara B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4260972/
https://ncbi.nlm.nih.gov/pubmed/25303528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.09.035
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