Discovery and characterization of gut microbiota decarboxylases that can produce the neurotransmitter tryptamine

Several recent studies describe the influence of the gut microbiota on host brain and behavior. However, the mechanisms responsible for microbiota-nervous system interactions are unknown. Using a combination of genetics, biochemistry, and crystallography, we identify and characterize two phylogeneti...

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Detalhes bibliográficos
Publicado no:Cell Host Microbe
Main Authors: Williams, Brianna B., Van Benschoten, Andrew H., Cimermancic, Peter, Donia, Mohamed S., Zimmermann, Michael, Taketani, Mao, Ishihara, Atsushi, Kashyap, Purna C., Fraser, James S., Fischbach, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4260654/
https://ncbi.nlm.nih.gov/pubmed/25263219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2014.09.001
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