Discovery and characterization of gut microbiota decarboxylases that can produce the neurotransmitter tryptamine

Several recent studies describe the influence of the gut microbiota on host brain and behavior. However, the mechanisms responsible for microbiota-nervous system interactions are unknown. Using a combination of genetics, biochemistry, and crystallography, we identify and characterize two phylogeneti...

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Dades bibliogràfiques
Publicat a:Cell Host Microbe
Autors principals: Williams, Brianna B., Van Benschoten, Andrew H., Cimermancic, Peter, Donia, Mohamed S., Zimmermann, Michael, Taketani, Mao, Ishihara, Atsushi, Kashyap, Purna C., Fraser, James S., Fischbach, Michael A.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4260654/
https://ncbi.nlm.nih.gov/pubmed/25263219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2014.09.001
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