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Fibroblasts probe substrate rigidity with filopodia extensions before occupying an area

Rigidity sensing and durotaxis are thought to be important elements in wound healing, tissue formation, and cancer treatment. It has been challenging, however, to study the underlying mechanism due to difficulties in capturing cells during the transient response to a rigidity interface. We have addr...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Wong, Stephanie, Guo, Wei-Hui, Wang, Yu-Li
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4260597/
https://ncbi.nlm.nih.gov/pubmed/25404288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1412285111
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