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Fascin Rigidity and L-plastin Flexibility Cooperate in Cancer Cell Invadopodia and Filopodia

Invadopodia and filopodia are dynamic, actin-based protrusions contributing to cancer cell migration, invasion, and metastasis. The force of actin bundles is essential for their protrusive activity. The bundling protein fascin is known to play a role in both invadopodia and filopodia. As it is more...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Van Audenhove, Isabel, Denert, Majken, Boucherie, Ciska, Pieters, Leen, Cornelissen, Maria, Gettemans, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861481/
https://ncbi.nlm.nih.gov/pubmed/26945069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.706937
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