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Reducing the genetic code induces massive rearrangement of the proteome
Expanding the genetic code is an important aim of synthetic biology, but some organisms developed naturally expanded genetic codes long ago over the course of evolution. Less than 1% of all sequenced genomes encode an operon that reassigns the stop codon UAG to pyrrolysine (Pyl), a genetic code vari...
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Publicado no: | Proc Natl Acad Sci U S A |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4260545/ https://ncbi.nlm.nih.gov/pubmed/25404328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1420193111 |
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