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Near-cognate suppression of amber, opal and quadruplet codons competes with aminoacyl-tRNA(Pyl) for genetic code expansion
Over 300 amino acids are found in proteins in nature, yet typically only 20 are genetically encoded. Reassigning stop codons and use of quadruplet codons emerged as the main avenues for genetically encoding non-canonical amino acids (NCAAs). Canonical aminoacyl-tRNAs with near-cognate anticodons als...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3488457/ https://ncbi.nlm.nih.gov/pubmed/23036644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2012.09.033 |
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