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BFR (bendamustine, fludarabine, and rituximab) allogeneic conditioning for chronic lymphocytic leukemia/lymphoma: reduced myelosuppression and GVHD

Myelosuppression, graft-versus-host disease (GVHD), and relapse remain major causes of morbidity after stem cell transplantation for relapsed lymphoma. In this phase 1/2 study, we tested the safety and efficacy of escalating doses of bendamustine (70, 90, 110, and 130 mg/m(2) per day for 3 days), co...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Khouri, Issa F., Wei, Wei, Korbling, Martin, Turturro, Francesco, Ahmed, Sairah, Alousi, Amin, Anderlini, Paolo, Ciurea, Stefan, Jabbour, Elias, Oran, Betul, Popat, Uday R., Rondon, Gabriela, Bassett, Roland L., Gulbis, Alison
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4260365/
https://ncbi.nlm.nih.gov/pubmed/25145344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-07-587519
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