Linking the Population Pharmacokinetics of Tenofovir and Its Metabolites With Its Cellular Uptake and Metabolism

Empirical pharmacokinetic models are used to explain the pharmacokinetics of the antiviral drug tenofovir (TFV) and its metabolite TFV diphosphate (TFV-DP) in peripheral blood mononuclear cells. These empirical models lack the ability to explain differences between the disposition of TFV-DP in HIV-i...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:CPT Pharmacometrics Syst Pharmacol
Main Authors: Madrasi, K, Burns, R N, Hendrix, C W, Fossler, M J, Chaturvedula, A
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2014
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4260001/
https://ncbi.nlm.nih.gov/pubmed/25390686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/psp.2014.46
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki