Population Pharmacokinetics of Tenofovir in HIV-1-Uninfected Members of Serodiscordant Couples and Effect of Dose Reporting Methods

Antiretroviral preexposure prophylaxis (PrEP) with once-daily dosing of tenofovir and tenofovir-emtricitabine was shown to be effective for preventing HIV-1 infection in individuals who had HIV-1-seropositive partners (the Partners PrEP Study). We developed a population pharmacokinetic model for ten...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Lu, Yanhui, Goti, Vineet, Chaturvedula, Ayyappa, Haberer, Jessica E., Fossler, Michael J., Sale, Mark E., Bangsberg, David, Baeten, Jared M., Celum, Connie L., Hendrix, Craig W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4997873/
https://ncbi.nlm.nih.gov/pubmed/27353269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00559-16
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