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Physiologically Based Pharmacokinetic Modeling and Simulation in Pediatric Drug Development

Increased regulatory demands for pediatric drug development research have fostered interest in the use of modeling and simulation among industry and academia. Physiologically based pharmacokinetic (PBPK) modeling offers a unique modality to incorporate multiple levels of information to estimate age-...

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Bibliografiske detaljer
Udgivet i:CPT Pharmacometrics Syst Pharmacol
Main Authors: Maharaj, A R, Edginton, A N
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4260000/
https://ncbi.nlm.nih.gov/pubmed/25353188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/psp.2014.45
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