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Nuclear export of cutaneous HPV8 E7 oncoprotein is mediated by a leucine-rich nuclear export signal via a CRM1 pathway

We recently determined that the nuclear import of cutaneous beta genus HPV8 E7 oncoprotein it is mediated by its zinc-binding domain via direct hydrophobic interactions with the FG nucleoporins Nup62 and Nup153 (Onder and Moroianu, 2014). Here we investigated the nuclear export of HPV8 E7 oncoprotei...

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Bibliografiske detaljer
Udgivet i:Virology
Main Authors: Onder, Zeynep, Chang, Vivian, Moroianu, Junona
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259873/
https://ncbi.nlm.nih.gov/pubmed/25463601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2014.10.012
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