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Nuclear import of cutaneous beta genus HPV8 E7 oncoprotein is mediated by hydrophobic interactions between its zinc-binding domain and FG nucleoporins

We have previously discovered and characterized the nuclear import pathways for the E7 oncoproteins of mucosal alpha genus HPVs, type 16 and 11. Here we investigated the nuclear import of cutaneous beta genus HPV8 E7 protein using confocal microscopy after transfections of HeLa cells with EGFP-8E7 a...

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Detalhes bibliográficos
Main Authors: Onder, Zeynep, Moroianu, Junona
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3894589/
https://ncbi.nlm.nih.gov/pubmed/24418548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2013.11.020
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