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Nuclear import of cutaneous beta genus HPV8 E7 oncoprotein is mediated by hydrophobic interactions between its zinc-binding domain and FG nucleoporins

We have previously discovered and characterized the nuclear import pathways for the E7 oncoproteins of mucosal alpha genus HPVs, type 16 and 11. Here we investigated the nuclear import of cutaneous beta genus HPV8 E7 protein using confocal microscopy after transfections of HeLa cells with EGFP-8E7 a...

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Dettagli Bibliografici
Autori principali: Onder, Zeynep, Moroianu, Junona
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3894589/
https://ncbi.nlm.nih.gov/pubmed/24418548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2013.11.020
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