SOXC proteins amplify canonical WNT signaling to secure nonchondrocytic fates in skeletogenesis

Canonical WNT signaling stabilizes β-catenin to determine cell fate in many processes from development onwards. One of its main roles in skeletogenesis is to antagonize the chondrogenic transcription factor SOX9. We here identify the SOXC proteins as potent amplifiers of this pathway. The SOXC genes...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Cell Biol
मुख्य लेखकों: Bhattaram, Pallavi, Penzo-Méndez, Alfredo, Kato, Kenji, Bandyopadhyay, Kaustav, Gadi, Abhilash, Taketo, Makoto M., Lefebvre, Véronique
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The Rockefeller University Press 2014
विषय:
Research Articles
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259807/
https://ncbi.nlm.nih.gov/pubmed/25452386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201405098
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