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BRCA1, FANCD2 and Chk1 are potential molecular targets for the modulation of a radiation-induced DNA damage response in bystander cells

Radiotherapy is an important treatment option for many human cancers. Current research is investigating the use of molecular targeted drugs in order to improve responses to radiotherapy in various cancers. The cellular response to irradiation is driven by both direct DNA damage in the targeted cell...

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Detalhes bibliográficos
Publicado no:Cancer Lett
Main Authors: Burdak-Rothkamm, Susanne, Rothkamm, Kai, McClelland, Keeva, Al Rashid, Shahnaz T., Prise, Kevin M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259524/
https://ncbi.nlm.nih.gov/pubmed/25304378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2014.09.043
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