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BRCA1, FANCD2 and Chk1 are potential molecular targets for the modulation of a radiation-induced DNA damage response in bystander cells

Radiotherapy is an important treatment option for many human cancers. Current research is investigating the use of molecular targeted drugs in order to improve responses to radiotherapy in various cancers. The cellular response to irradiation is driven by both direct DNA damage in the targeted cell...

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Podrobná bibliografie
Vydáno v:Cancer Lett
Hlavní autoři: Burdak-Rothkamm, Susanne, Rothkamm, Kai, McClelland, Keeva, Al Rashid, Shahnaz T., Prise, Kevin M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259524/
https://ncbi.nlm.nih.gov/pubmed/25304378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2014.09.043
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