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New molecular targets in radiotherapy: DNA damage signalling and repair in targeted and non-targeted cells
Ionising radiation plays a key role in therapy due to its ability to directly induce DNA damage, in particular DNA double-strand breaks leading to cell death. Cells have multiple repair pathways which attempt to maintain genomic stability. DNA repair proteins have become key targets for therapy, usi...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2855957/ https://ncbi.nlm.nih.gov/pubmed/19835868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2009.09.068 |
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