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Behavioral Phenotyping of Parkin-Deficient Mice: Looking for Early Preclinical Features of Parkinson's Disease

There is considerable evidence showing that the neurodegenerative processes that lead to sporadic Parkinson's disease (PD) begin many years before the appearance of the characteristic motor symptoms. Neuropsychiatric, sensorial and cognitive deficits are recognized as early non-motor manifestat...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Rial, Daniel, Castro, Adalberto A., Machado, Nuno, Garção, Pedro, Gonçalves, Francisco Q., Silva, Henrique B., Tomé, Ângelo R., Köfalvi, Attila, Corti, Olga, Raisman-Vozari, Rita, Cunha, Rodrigo A., Prediger, Rui D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259468/
https://ncbi.nlm.nih.gov/pubmed/25486126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114216
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