SapC-DOPS-induced lysosomal cell death synergizes with TMZ in glioblastoma

SapC-DOPS is a novel nanotherapeutic that has been shown to target and induce cell death in a variety of cancers, including glioblastoma (GBM). GBM is a primary brain tumor known to frequently demonstrate resistance to apoptosis-inducing therapeutics. Here we explore the mode of action for SapC-DOPS...

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發表在:Oncotarget
Main Authors: Wojton, Jeffrey, Meisen, Walter Hans, Jacob, Naduparambil K., Thorne, Amy Haseley, Hardcastle, Jayson, Denton, Nicholas, Chu, Zhengtao, Dmitrieva, Nina, Marsh, Rachel, Van Meir, Erwin G., Kwon, Chang-Hyuk, Chakravarti, Arnab, Qi, Xiaoyang, Kaur, Balveen
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2014
主題:
Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259431/
https://ncbi.nlm.nih.gov/pubmed/25210852
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