SapC-DOPS-induced lysosomal cell death synergizes with TMZ in glioblastoma

SapC-DOPS is a novel nanotherapeutic that has been shown to target and induce cell death in a variety of cancers, including glioblastoma (GBM). GBM is a primary brain tumor known to frequently demonstrate resistance to apoptosis-inducing therapeutics. Here we explore the mode of action for SapC-DOPS...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Wojton, Jeffrey, Meisen, Walter Hans, Jacob, Naduparambil K., Thorne, Amy Haseley, Hardcastle, Jayson, Denton, Nicholas, Chu, Zhengtao, Dmitrieva, Nina, Marsh, Rachel, Van Meir, Erwin G., Kwon, Chang-Hyuk, Chakravarti, Arnab, Qi, Xiaoyang, Kaur, Balveen
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2014
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259431/
https://ncbi.nlm.nih.gov/pubmed/25210852
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires