Systemic Delivery of SapC-DOPS Has Antiangiogenic and Antitumor Effects Against Glioblastoma

Saposin C-dioleoylphosphatidylserine (SapC-DOPS) nanovesicles are a nanotherapeutic which effectively target and destroy cancer cells. Here, we explore the systemic use of SapC-DOPS in several models of brain cancer, including glioblastoma multiforme (GBM), and the molecular mechanism behind its tum...

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Detalhes bibliográficos
Main Authors: Wojton, Jeffrey, Chu, Zhengtao, Mathsyaraja, Haritha, Meisen, Walter H, Denton, Nicholas, Kwon, Chang-Hyuk, Chow, Lionel ML, Palascak, Mary, Franco, Robert, Bourdeau, Tristan, Thornton, Sherry, Ostrowski, Michael C, Kaur, Balveen, Qi, Xiaoyang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734660/
https://ncbi.nlm.nih.gov/pubmed/23732993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.114
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