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Ischemia and Reperfusion Induce Differential Expression of Calpastatin and Its Homologue High Molecular Weight Calmodulin-Binding Protein in Murine Cardiomyocytes
In the heart, calpastatin (Calp) and its homologue high molecular weight calmodulin-binding protein (HMWCaMBP) regulate calpains (Calpn) by inhibition. A rise in intracellular myocardial Ca(2+) during cardiac ischemia activates Calpn thereby causing damage to myocardial proteins, which leads to myoc...
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| Publicado no: | PLoS One |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4259361/ https://ncbi.nlm.nih.gov/pubmed/25486053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114653 |
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