Integrins protect cardiomyocytes from ischemia/reperfusion injury

Ischemic damage is recognized to cause cardiomyocyte (CM) death and myocardial dysfunction, but the role of cell-matrix interactions and integrins in this process has not been extensively studied. Expression of α7β1D integrin, the dominant integrin in normal adult CMs, increases during ischemia/repe...

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Autori principali: Okada, Hideshi, Lai, N. Chin, Kawaraguchi, Yoshitaka, Liao, Peter, Copps, Jeffrey, Sugano, Yasuo, Okada-Maeda, Sunaho, Banerjee, Indroneal, Schilling, Jan M., Gingras, Alexandre R., Asfaw, Elizabeth K., Suarez, Jorge, Kang, Seok-Min, Perkins, Guy A., Au, Carol G., Israeli-Rosenberg, Sharon, Manso, Ana Maria, Liu, Zheng, Milner, Derek J., Kaufman, Stephen J., Patel, Hemal H., Roth, David M., Hammond, H. Kirk, Taylor, Susan S., Dillmann, Wolfgang H., Goldhaber, Joshua I., Ross, Robert S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784521/
https://ncbi.nlm.nih.gov/pubmed/24091324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI64216
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