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Comparison of Multiple Displacement Amplification (MDA) and Multiple Annealing and Looping-Based Amplification Cycles (MALBAC) in Single-Cell Sequencing

Single-cell sequencing promotes our understanding of the heterogeneity of cellular populations, including the haplotypes and genomic variability among different generation of cells. Whole-genome amplification is crucial to generate sufficient DNA fragments for single-cell sequencing projects. Using...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Chen, Minfeng, Song, Pengfei, Zou, Dan, Hu, Xuesong, Zhao, Shancen, Gao, Shengjie, Ling, Fei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259343/
https://ncbi.nlm.nih.gov/pubmed/25485707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114520
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