Deleted in Breast Cancer 1 (DBC1) is a Suppressor of B cell Activation by Negatively Regulating Alternative NF-κB Transcriptional Activity

CD40 and BAFF receptor (BAFFR) signaling plays important roles in B cell proliferation and immunoglobulin production. In this study we found that B cells from mice with deletion of Dbc1 gene (Dbc1(−/−)) show elevated proliferation, and IgG1 and IgA production upon in vitro CD40 and BAFF, but not BCR...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Immunol
Päätekijät: Kong, Sinyi, Thiruppathi, Muthusamy, Qiu, Quan, Lin, Zhenghong, Dong, Hongxin, Chini, Eduardo N., Prabhakar, Bellur S., Fang., Deyu
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259264/
https://ncbi.nlm.nih.gov/pubmed/25362179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401798
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