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Deleted in Breast Cancer 1 (DBC1) is a Suppressor of B cell Activation by Negatively Regulating Alternative NF-κB Transcriptional Activity
CD40 and BAFF receptor (BAFFR) signaling plays important roles in B cell proliferation and immunoglobulin production. In this study we found that B cells from mice with deletion of Dbc1 gene (Dbc1(−/−)) show elevated proliferation, and IgG1 and IgA production upon in vitro CD40 and BAFF, but not BCR...
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| Publicado no: | J Immunol |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4259264/ https://ncbi.nlm.nih.gov/pubmed/25362179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401798 |
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