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Role of urokinase plasminogen activator and plasminogen activator inhibitor mRNA expression as prognostic factors in molecular subtypes of breast cancer

BACKGROUND: Protein levels of urokinase plasminogen activator (uPA) and its inhibitor (PAI-1) determined by enzyme-linked immunosorbent assay from fresh-frozen tumor tissue have been evaluated as prognostic factors in prospectively randomized trials in breast cancer. However, the role of uPA and PAI...

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Détails bibliographiques
Publié dans:Onco Targets Ther
Auteurs principaux: Witzel, Isabell, Milde-Langosch, Karin, Schmidt, Marcus, Karn, Thomas, Becker, Sven, Wirtz, Ralph, Rody, Achim, Laakmann, Elena, Schütze, Dina, Jänicke, Fritz, Müller, Volkmar
Format: Artigo
Langue:Inglês
Publié: Dove Medical Press 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259258/
https://ncbi.nlm.nih.gov/pubmed/25506225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S65344
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