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Transduction of ferret airway epithelia using a pre-treatment and lentiviral gene vector

BACKGROUND: The safety and efficiency of gene therapies for cystic fibrosis (CF) need to be assessed in pre-clinical models. Using the normal ferret, this study sought to determine whether ferret airway epithelia could be transduced with a lysophosphatidylcholine (LPC) pre-treatment followed by a VS...

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Detalhes bibliográficos
Publicado no:BMC Pulm Med
Main Authors: Cmielewski, Patricia, Farrow, Nigel, Donnelley, Martin, McIntyre, Chantelle, Penny-Dimri, Jahan, Kuchel, Tim, Parsons, David
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258949/
https://ncbi.nlm.nih.gov/pubmed/25413892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2466-14-183
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