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Lysophosphatidylcholine as an adjuvant for lentiviral vector mediated gene transfer to airway epithelium: effect of acyl chain length

BACKGROUND: Poor gene transfer efficiency has been a major problem in developing an effective gene therapy for cystic fibrosis (CF) airway disease. Lysophosphatidylcholine (LPC), a natural airway surfactant, can enhance viral gene transfer in animal models. We examined the electrophysiological and p...

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Detalhes bibliográficos
Main Authors: Cmielewski, Patricia, Anson, Don S, Parsons, David W
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905357/
https://ncbi.nlm.nih.gov/pubmed/20569421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-11-84
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