Inhibition of STAT3-interacting protein 1 (STATIP1) promotes STAT3 transcriptional up-regulation and imatinib mesylate resistance in the chronic myeloid leukemia

BACKGROUND: Signal transducer and activator of transcription 3 (STAT3) is an important transcriptional factor frequently associated with the proliferation and survival of a large number of distinct cancer types. However, the signaling pathways and mechanisms that regulate STAT3 activation remain to...

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Publicado en:BMC Cancer
Autores principales: Mencalha, André L, Corrêa, Stephany, Salles, Daniela, Du Rocher, Bárbara, Santiago, Marcelo F, Abdelhay, Eliana
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258947/
https://ncbi.nlm.nih.gov/pubmed/25417721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-866
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